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| Fuhua Huang,Liangpeng Li,Wei Qin,Cunhua Su,Liming Wang,Liqiong Xiao,Xin Chen.Journal of Biomedical Research,2016,30(5):/span> |
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| Partial aortic root remodeling for root reconstruction in patients with acute type A dissection |
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Received:July 19, 2015Revised:October 05, 2015
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DOI：10.7555/JBR.30.20150097
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Keywords：aortic dissection, aortic root remodeling, valve function
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Grant Program：
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| Author |
Institution |
| Fuhua Huang |
Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital affiliated to Nanjing Medical University,Nanjing Cardiovascular Disease Research Institute, Nanjing, Jiangsu , China |
| Liangpeng Li |
Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital affiliated to Nanjing Medical University,Nanjing Cardiovascular Disease Research Institute, Nanjing, Jiangsu , China |
| Wei Qin |
Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital affiliated to Nanjing Medical University,Nanjing Cardiovascular Disease Research Institute, Nanjing, Jiangsu , China |
| Cunhua Su |
Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital affiliated to Nanjing Medical University,Nanjing Cardiovascular Disease Research Institute, Nanjing, Jiangsu , China |
| Liming Wang |
Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital affiliated to Nanjing Medical University,Nanjing Cardiovascular Disease Research Institute, Nanjing, Jiangsu , China |
| Liqiong Xiao |
Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital affiliated to Nanjing Medical University,Nanjing Cardiovascular Disease Research Institute, Nanjing, Jiangsu , China |
| Xin Chen |
Department of Thoracic and Cardiovascular Surgery, Nanjing Hospital affiliated to Nanjing Medical University,Nanjing Cardiovascular Disease Research Institute, Nanjing, Jiangsu , China |
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| Abstract ： |
| In the present study, we reported our experience with partial aortic root remodeling for root reconstruction in patients with acute type A dissection, which involves in non-coronar sinus and/or the right coronary sinus with just one trimmed Dacron graft. Between February 2001 and May 2010, we performed partial aortic root remode-ling in 40 patients, who underwent emergency surgical intervention. The dissected sinuses were excised leaving a 3-5 mm rim of the aortic wall from the attached aortic valve cusps. A short piece (4-5 cm) of collagen coated woven polyester vascular prosthesis was trimmed with one or two "tongues" to reconstruct the non-coronary sinus and/ or the right coronary sinus, but without using separated patches. Additional procedures were including hemi-arch replacement in 11 patients, and total arch replacement plus stent-elephant trunk in 20 patients. The mean follow-up time was 36.4±3.6 months. In-hospital mortality was only 5.0% (2/40); furthermore, 3 (8.6%) patients underwent re-operation of the aortic valve and 2 (5.7%) patients died during follow-up. At the end of follow-up, trivial or no aortic regurgitation was found in 33 patients, but mild aortic regurgitation was found in 2 patients. Our data suggest that the early and mid-term results of partial aortic root remodeling were favorable, and it restored valve durability and function. Thus, the use of technique for root reconstruction in patients with acute type A dissection should be vigorously encouraged.
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