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Thomas M. Munger,Li-Qun Wu,Win K. Shen.Journal of Biomedical Research,2014,28(1):1-17
Atrial fibrillation
DOI:10.7555/JBR.28.20130191
Keywordsatrial fibrillation, arrhythmias, cardiac, stroke, dementia, heart failure
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Thomas M. Munger Heart Rhythm Services, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Li-Qun Wu Department of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University of Medicine, Shanghai , China
Win K. Shen Division of Cardiovascular Diseases, Mayo Clinic, Phoenix, AZ 85054, USA
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Abstract
Atrial fibrillation is the most common arrhythmia affecting patients today. Disease prevalence is increasing at an alarming rate worldwide, and is associated with often catastrophic and costly consequences, including heart failure, syncope, dementia, and stroke. Therapies including anticoagulants, anti-arrhythmic medications, devices, and non-pharmacologic procedures in the last 30 years have improved patients' functionality with the disease. Nonetheless, it remains imperative that further research into AF epidemiology, genetics, detection, and treatments continues to push forward rapidly as the worldwide population ages dramatically over the next 20 years.
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